Mechanisms of action

Iodine is used in medical practice for over 150 years for the treatment of wounds, the surgical field in dentistry and for the treatment of skin diseases. It reacts not only with proteins of microorganisms, but also the microorganism to form a typical film on the surface of the wound, which prevents the penetration of pathogenic bacteria. However, quite often just under the skin there is inflammatory.

Domestic researchers have developed a drug YODDITSERIN, which penetrates deeply into the lesion tissue. What is his zest and edge over other iodine-containing drugs?

Its distinguishing feature - no irritating effect, and the ability to brand viagra penetrate deeply into tissue, where the breed germs of inflammatory processes. YODDITSERIN makes full use of certain antimicrobial action of iodine directly in living tissues without damaging them. In the finished dosage form of germicidal iodine cation, solvated by a monomolecular layer of aprotic solvents - dimethyl sulfoxide, is balanced by the anion, which is not dimethyl sulfoxide solvated. As the dissolution medium used triatomic alcohol glycerin, do not react with iodine ions and dimethyl sulfoxide. Such a stable ion system with an anhydrous phase in the treatment of patients with purulent infection dynamically transformed. She very quickly penetrates into tissues, bypassing the blood and lymphatic flow, due to the lipophilicity of dimethyl sulfoxide, while attending his desolvation, thus liberated active iodine cations, which are the focus of purulent infection have an antimicrobial effect. The depth of penetration of the drug by the time of his application. When working with cultures of microorganisms YODDITSERIN for speed and minimal bactericidal concentrations exceed counterparts. The drug penetrates the purulent inflammatory foci, does not cause pain and tissue irritation. YODDITSERIN applied topically (tampons, turundas, wipes, wraps, etc.), and is suitable for application to mucous membranes.

The drug was widely used in surgical practice, it can also be used in combination with other drugs, such as ointments, which include antibiotics. Drug resistance of pathogens of purulent infection in YODDITSERIN does not develop. Some of the advantages by which physicians choose this drug, it should be emphasized that all the components YODDITSERINA pharmacologically active. He has a broad spectrum of antimicrobial activity, has anti-edematous, antinekroticheskim and anti-inflammatory action.

In various phases of wound healing process is also effective Eton gel 1% of JSC "Pharmak. It is bactericidal, and anesthetic wound-healing effect. Eton gel 1% cleans wounds, promotes granulation, which leads to faster healing of the wound surface. Its successful use as a phase of alteration, and during the granulation than the drug and is different from most of ointments used in surgical practice.

According to the chemical structure of Eton refers to a group bischetvertichnoe ammonium compounds. The mechanism of antimicrobial action of these substances is a change in the synthesis of cell wall components of pathogens.

Eton gel 1% stimulates the regeneration, cleans staphylococcal toxin, has anesthetic action.

Given the multivalency of the drug, its use is indicated for treatment of purulent surgical wounds, postoperative wounds, burns, II and IIIA degrees of trophic ulcers and prevention of infectious complications in household injuries.

The lesion causing the gel 1-2 times a day (until negative results of microbiological investigations) within 1-2 weeks. After the standard treatment of trophic ulcers, wounds and burns gel put on the wound surface with a sterile gauze bandage. Tampons impregnated with gel, fill the cavity of septic wounds after surgical treatment, or irrigation with antiseptic solution, and gauze turundas gel injected into the fistula. In the treatment of septic wounds gel using 1 time per day, for treatment of burns - every day or 2-3 times per week depending on the condition of the wound. The amount of drug determined by the degree of purulent exudate, the duration of treatment depends on the purification and healing.

Application Eton gel 1% is shown as in the phases of alteration and exudation, and at the stage of regeneration, which avoids the need for multiple drugs with different mechanisms of action and at the same time, greatly enhance the effectiveness of treatment.

Effectiveness of the drug is determined not only Eton - the active substance, but also adjuvants that promote deeper penetration of the drug in the tissue and enhance its therapeutic activity.

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